Personal Staff Webpage:
Name: Sunil K. Kakarla, M.S.
Biography
Ph.D. Student Biomedical Sciences
Marshall University, present
M.S. Biology
Marshall University, 2007
BVSc & AH (Equivalent of D.V.M)
CvSc, Tirupati India, 2003
Current Research Area / Interests
My research is mainly focused on understanding the efficacy of chronic acetaminophen treatment in attenuating aging associated increases in cardiac ROS and apoptosis.
Recent Publications
Miazong Wu, Anjaiah Katta, Murali K. Gadde, Hua Liu, Sunil K. Kakarla, Satyanarayana Paturi, Kevin M. Rice, Ernest M Walker Jr, and Eric R Blough; Aging-associated dysfunction of Akt / protein kinase B: S-nitrosylation and acetaminophen intervention. (accepted-PLOS BIOLOGY 2009)
Rabaa M. AL-Rousan, Satyanarayana Paturi, Joseph Laurino, Sunil K. Kakarla, Anil K Gutta, Ernest M. Walker, and Eric R. Blough. 2009. Deferasirox Removes Cardiac Iron and Attenuates Oxidative Stress in the Iron-Overloaded Gerbil. (accepted -American journal of Haematology)
Katta A, Sunil K. Kakarla, Wu M, Meduru S, Desai DH, Rice KM, Blough ER. Lean and obese Zucker rats exhibit different patterns of p70s6 kinase regulation in the tibialis anterior muscle in response to high-force muscle contraction. Muscle Nerve. 2009 Apr;39(4):503-11.
Wu M, Desai DH, Sunil K. Kakarla, Katta A, Paturi S, Gutta AK, Rice KM, Walker EM Jr, Blough ER. Acetaminophen prevents aging-associated hyperglycemia in aged rats: effect of aging-associated hyperactivation of p38-MAPK and ERK1/2. Diabetes Metab Res Rev. 2009 Mar;25(3):279-86.
Katta A, Preston DL, Sunil K. Kakarla, Asano S, Meduru S, Mupparaju SP, Yokochi E, Rice KM, Desai DH, Blough ER. Diabetes alters contraction-induced mitogen activated protein kinase activation in the rat soleus and plantaris. Exp Diabetes Res. 2008;2008:738101
.
Asano S, Rice KM, Sunil K. Kakarla, Katta A, Desai DH, Walker EM, Wehner P, Blough ER. Aging influences multiple indices of oxidative stress in the heart of the Fischer 344/NNia x Brown Norway/BiNia rat. Redox Rep. 2007;12(4):167-80.
Rice KM, Desai DH, Sunil K. Kakarla, Katta A, Preston DL, Wehner P, Blough ER. Diabetes alters vascular mechanotransduction: pressure-induced regulation of mitogen activated protein kinases in the rat inferior vena cava. Cardiovasc Diabetol. 2006 Sep 8;5:18.
